مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma

مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma

… دانلود …

مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma دارای 5 صفحه می باشد و دارای تنظیمات در microsoft word می باشد و آماده پرینت یا چاپ است

فایل ورد مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma کاملا فرمت بندی و تنظیم شده در استاندارد دانشگاه و مراکز دولتی می باشد.

توجه : در صورت  مشاهده  بهم ريختگي احتمالي در متون زير ،دليل ان کپي کردن اين مطالب از داخل فایل ورد مي باشد و در فايل اصلي مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma،به هيچ وجه بهم ريختگي وجود ندارد


بخشی از متن مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma :

سال انتشار : 2015

تعداد صفحات : 5

Background: Patients with refractory or relapsed multiple myeloma are considered to have a very poorprognosis, and new regimens are needed to improve this setting. Pomalidomide is a new immunomodulatorydrug with high in vitro potency. Immunomodulatory drugs are hypothesized to act through multiple mechanisms.Here we performed a systemic analysis to evaluate pomalidomide-based chemotherapy (pomalidomide incombination with low-dose dexamethasone) as salvage treatment for patients with refractory and relapsed multiplemyeloma. Methods: Clinical studies evaluating the efffectiveness of pomalidomide based regimens on responseand safety for patients with refractory and relapsed multiple myeloma were identified using a predefined searchstrategy. Pooled response rate (RR) of treatment were calculated. Results: For pomalidomide based regimens,4 clinical studies which including 291 patients with refractory and relapsed multiple myeloma were consideredeligible for inclusion. Systemic analysis suggested that, in all patients, pooled RR was 41.2% (120/291). Majoradverse effects were hematologic toxicity, including grade 1 or 2 anemia, leucopenia and thrombocytopeniawith pomalidomide based treatment. No treatment related death occurred. Conclusion: This pooled analysissuggests that pomalidomide in combination with low-dose dexamethasone is active with good tolerability intreating patients with refractory or relapsed multiple myeloma.

به پیشرفته ترین فروشگاه فایل خوش آمدید.جهت مشاهده توضیحات کامل فایل مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma روی لینک ادامه مطلب کلیک کنید.

مقاله Pooled Analysis of Pomalidomide for Treating Patients with Multiple Myeloma